MALAT1 is highly expressed in inflammation‐activated macrophages, interacts with NF‐κB, inhibits TLR signaling, and lowers TNF‐α, IL‐6 and other inflammatory factors,49 MALAT1/miR‐146a axis is contributed to the stimulation of inflammatory response in ALI.50 Here, MALAT1 is linked to acute respiratory distress syndrome.