SPTA1 and Alpha-thalassemia: Five patients underwent whole exome sequencing (WES) in addition to SCD diagnosis, which revealed the following mutations: G6PD (n = 2), SPTA1 (n = 1), alpha thalassemia (n = 1), a compound heterozygous mutation causing sickle beta thalassemia (n = 1), and a FANCA variant of unknown significance (n = 1).