As shown in Figure 2 and Supplementary Table 3, for the cALT-associated SNPs, IVW MR analysis with a random-effects model demonstrated no significant causal relationship between NAFLD and the risk of kidney stones in both the FinnGen consortium and the UK Biobank (UKBB) study (FinnGen: OR: 1.02, 95% CI: 0.94-1.11, p = 0.632; UKBB: OR: 1.000, 95% CI: 0.998-1.002, p = 0.852). Here, CETN2 is linked to nephrolithiasis.