Using Venn tool, we first showed 22 shared DEGs between RA and LUAD (Figure 4A), including ACTC1, ANKRD1, C10orf71, CCN6, CSF3, and FABP4 etc. Then, we performed univariate Cox analysis (Figure 4B) and found that only one gene, CCN6, was the candidate gene to affect overall survival (OS). The gene discussed is ACTC1; the disease is rheumatoid arthritis.