ASA 4 patients showed an increased risk of developing chronic cutaneous fistula compared to ASA 3 patients (OR 4.8, 95 CI 1.1 to 21.1, p = 0.03), while the type of resection, age, sex, obesity, the intake of antiplatelet and anticoagulant agents, partial thromboplastin time, prothrombin time and relevant postoperative bleeding did not influence the infection recurrence. Here, F2 is linked to infection.