Immunology response pathway analysis showed lymphocyte activation, cytokine signaling, inflammasomes, Th17 differentiation, Th2 differentiation, NF-kB signaling, and TNF family signaling as significantly upregulated pathways in the TOFU-DCs + PD-1 treated GL261 tumor-bearing mice compared to untreated (Fig. 4f). Here, PDCD1 is linked to neoplasm.