Univariate survival analysis revealed the following 13 clinicopathological factors related to MPM prognosis: surgery history, radiotherapy history, KPS, preoperative CA 125 level, PS (Fig. 1B), PCI, CC score, RBC transfusion, ascites, pathological type, lymphatic metastasis, Ki-67 index and SAEs (all P < 0.05). The gene discussed is MKI67; the disease is Ascites.