TGFB1 and neoplasm: To further verify the role of the TGF-b1/Smad2/3 pathway in FBXO28 knockdown-mediated tumor inhibition, we performed rescue experiments in A2780 and SKOV3 cells with FBXO28 knockdown by transfecting a TGF-b1 overexpression plasmid to upregulate TGF-b1 expression.