In the tumor microenvironment, mHAdLyp.sT treated group had increased expression of IL-12 on both day 14 and day 25, and IFN-γ on day 25 (Fig. 3B, day 14; Fig. 3D, day 25; IL-12, the third panels; IFN-γ, the fourth panels; P < 0.05 or 0.01 vs buffer). Here, IFNG is linked to neoplasm.