To assess the expression level of RanGAP1 in cancer, we utilized The Cancer Genome Atlas (TCGA) database and observed elevated levels of RanGAP1 in several cancers, including Colon Adenocarcinoma (COAD) and Rectum Adenocarcinoma (READ) (Fig. 1A, B, Fig. S1A). Here, RANGAP1 is linked to rectum adenocarcinoma.