There were frequent interactions between tumour-residing CCR7+ DCs and Kaede-red+CD3+CD8+ T cells, often within a perivascular niche, including proliferating (Ki-67+)4-1BB+ cytotoxic cells (Fig. 5e, Supplementary Fig. 9g–i), consistent with a role for CCR7+ DCs in regulating anti-tumour cytolytic activity. This evidence concerns the gene MKI67 and neoplasm.