Moreover, in scRNA-seq of breast cancer (Supplementary Fig. 1d, 11h)24, CCR7_DCs from tumours that successfully underwent clonal T cell expansion following treatment with anti-PD-1 antibodies were enriched in transcripts associated with our ICB-induced Ccr7_DC.2 cluster, versus non-responders (Fig. 6f). Here, PDCD1 is linked to breast cancer.