It's also worth mentioning that we found some patients showed improved hepatic or renal function at the end of caspofungin treatment, such as a decrease in ALT, AST, ALP, γ-GGT, or an increase in TP, albumin which could potentially be attributed to the comprehensive effect of infection control, HA infusion, the treatment of anti-inflammatory and liver-protective. This evidence concerns the gene GPT and infection.