Pathway analysis revealed that the top 10 pathways at 17 months of age included many pathways related to collagen (e.g. GP6 signaling pathway and hepatic fibrosis hepatic stellate cell activation) and immune cell signaling (e.g. pathogen induced cytokine storm signaling pathway and neutrophil extracellular trap signaling pathway) (Fig. 4H). This evidence concerns the gene GP6 and Hepatic fibrosis.