NF2 and schwannomatosis: NF2 status differed significantly between the two transcriptional subtypes: SP-EPN subtype A comprised cases with NF2-related schwannomatosis, NF2 mutations only in the tumor, and tumors with no NF2 mutation detected, whereas SP-EPN subtype B only consisted of cases with no NF2 mutation detected, (p < 0.001; Fig. 4c).