Notably, PFS differed significantly between patients with tumors harboring NF2 mutations that were only detected in the tumor and patients with SP-EPN with no NF2 mutation detected (p = 0.009; Fig. 6b) as well as between cases with no NF2 mutation detected and NF2-related schwannomatosis patients (p = 0.02; Fig. 6b). Here, NF2 is linked to schwannomatosis.