While NF2 mutations in NF2-related schwannomatosis-related tumors showed similar genomic distribution in all three entities (SP-EPN, schwannoma and meningioma), mutations in sporadic schwannomas (or schwannoma without germline information) were located more towards the C-terminal end compared to SP-EPN with NF2 mutations in tumor material (Suppl. Here, NF2 is linked to schwannomatosis.