They also had a lower PaO2/FiO2 ratio, lower platelet levelsthan non-COVID-19 patients, and more metabolic changes, such as higherlevels of blood glucose, C-reactive protein, and lactic dehydrogenase.Patients with non-COVID-19 acute respiratory failure had a higher prevalenceof chronic obstructive pulmonary disease/asthma and cardiopathy. This evidence concerns the gene CRP and chronic obstructive pulmonary disease.