The association of these factors means, for this audience, the possibility of occurrence of hyper-inflammatory responses (leukocytosis, neutrophilia and elevated levels of C-reactive protein and ferritin), as well as organic and coagulation dysfunctions (increased plasma glucose, altered serum creatinine and lactate dehydrogenase and increased D-dimer levels)(2,18). This evidence concerns the gene CRP and Increased total leukocyte count.