CGAS and neoplasm: In brief, the ZnFe2O4 nanoparticle would release Fe3+ and Zn2+ in the tumour cytoplasm by responding to the high level of GSH, during which process, Fe3+ induced intracellular ROS to achieve DNA leakage and Zn2+ promoted cGAS‐DNA phase separation as well as enhanced the cGAS enzyme activity.[23] In addition, the released PTX inhibited the tumour cell mitosis, which further strengthened the activation of cGAS/STING pathway (Figure 1A).