HSP90B2P and neoplasm: HSP, including HSP70 and HSP90, can awake the inherent defense mechanism of tumor cells under hyperthermia‐based treatments, is important for the tumor cells’ thermoresistance.[49] Hence, the restriction of ATP supply by GOx could reverse the thermoresistance of tumor cells, augmenting the therapeutic efficacy of photothermal hyperthermia at low temperature (about 43°C) induced by 2D AQDs upon 808 nm laser irradiation.