Key cytokines and chemokines and their receptors in addition to growth regulators (Areg, Csf1, Gdf6, Nrg1, Pdgfa, Spp1), adhesion (F11r, Fn1) and stemness modulators (Hdac7, Lefty1, Procr), and genes associated with progressive disease (Apoa2, Apol7a, Inhba, Mif, Nos2, Olr1, Prl, Tnfsf9, S100a8) were upregulated in the OFB with the cancer cells. The gene discussed is S100A8; the disease is cancer.