also reported a second biomarker combination which performed equally well in discriminating TBM and non-TBM, which included soluble ICAM-1, myeloperoxidase, CXCL8 (IL-8), and IFNγ (41), suggesting a key role for ICAM-1 in TBM pathology. The gene discussed is ICAM1; the disease is meningeal tuberculosis.