Karunarathna et al. (2016); Wang et al. (2016) independently found FOXM1 interacts with OTUB1. They further showed OTUB1 decreases FOXM1 ubiquitination and promotes FOXM1 protein stability. Wang et al. (2016) also provided evidence that OTUB1 directly removes K48-linked ubiquitination from FOXM1. Katzenellenbogen et al. (2023) showed OTUB1 promotes breast cancer cell proliferation through FOXM1. This evidence concerns the gene FOXM1 and breast cancer.