The expression of all PDGF ligands (PDGF-A, PDGF-B, PDGF-C, and PDGF-D) and both cell surface receptors, PDGFR-α and PDGFR-β, have been demonstrated in GBM (Pearson and Regad, 2017). This evidence concerns the gene PDGFRA and glioblastoma.