GPX4 and cancer: We developed Pt‐R OC models through repeated exposure of OC cell lines to cytotoxic doses of Pt.[8, 34] Compared to platinum‐sensitive (Pt‐S) cells, the Pt‐R cells demonstrated increased antioxidant capacity (upregulated GPx4), increased susceptibility to ferroptosis,[8] and increased fatty acid (FA) accumulation and import.[9] Given the reported dependence of other cancer cells to cholesterol,[13, 35, 36] we measured intracellular total cholesterol levels through an Amplex Red colorimetric assay in OC Pt‐S and Pt‐R cells.