To explore the role of ARHGAP35 in the malignant progression of NPC, we overexpressed ARHGAP35 in CNE2 and C666-1 cells (Figure S3A, B) and then found that NPC cells overexpressing ARHGAP35 showed significant inhibitory effects on proliferation and migration. The gene discussed is ARHGAP35; the disease is nasopharyngeal carcinoma.