According to existing research on m6A modification, in leukemia cells, the expression of phosphofructokinase platelets (PFKP) and lactate dehydrogenase B (LDHB) (two key glycolytic genes) was increased through the mediation of FTO/m6A/YTH m6A RNA binding protein 2 (YTHDF2), thus promoting aerobic glycolysis in leukemia cells and significantly inhibiting the progression of leukemia [11]. The gene discussed is FTO; the disease is leukemia.