ALKBH5 and nasopharyngeal carcinoma: To verify whether the above changes in the NPC malignant phenotype were caused by the cooperative “demethylation” of m6A-mediated gene expression by FTO and ALKBH5, we compared the distribution of m6A in the shCtrl, shFTO, shALKBH5 and shFTO+shALKBH5 groups to explore the relationship between them.