We treated fibroblast (MRC-5), lymphatic endothelial cell (LEC), and B-cell lymphomas (Akata-, BJAB, Daudi) with immune stimulants including lipopolysaccharide (LPS), CpG DNA, poly I:C, IFN-β and -γ (Fig. EV4). This evidence concerns the gene IFNB1 and B-cell non-Hodgkin lymphoma.