NDUFV1 and melanoma: LONP1 over-expression results in impaired complex I assembly in melanoma cells, upregulation of NDUFB6,8,10 and 11, and downregulation of NDUFV1, NDUFV2, NDUFS3 and NDUFS7 (Pinti et al, 2016; Quiros et al, 2014).