Seven of these genes were novel for their association with PD, while twelve of them (i.e. ARHGAP27, FAM200B, TMEM175, CD38, ZSWIM7, GPNMB, STX4, KANSL1, ADORA2B, KAT8, MMRN1, PRSS36) were previously identified by Alvarado et al.21, validating our approach. The gene discussed is ARHGAP27; the disease is Parkinson disease.