Two of the 49 traits were PD and proxy-PD (first-degree relative), which is consistent with the identification of the genes (LINC02210, KANSL1, TMEM175, CD38, MMRN1, RAB29, STX4, PRSS36, GPNMB, NUPL2, KAT8, KLHL7-AS1, and ARHGAP27) being causally linked to PD, as the loci containing the regulatory sceQTLs have previously been associated with PD risk through GWAS. This evidence concerns the gene STX4 and Parkinson disease.