In subsequent experiments, we found that LINC02609 shRNA aggravated the suppression of proliferation and metastasis by HIF2α and that APOL1 partly reversed the suppression of ccRCC by HIF2α shRNA or/and LINC02609 shRNA (Fig. 7B). The gene discussed is LINC02609; the disease is nonpapillary renal cell carcinoma.