Unlike the above studies, another undifferentiated study denied the association between glomerular filtration rate and the risk of prostate cancer development, Kim et al. confirmed that the percentage of free prostate-specific antigen was not correlated with glomerular filtration rate by correlation and multivariate regression analyses of percentage of free prostate-specific antigen, body mass index, prostate size, and glomerular filtration rate of 91 patients with prostate cancer [24]. The gene discussed is KLK3; the disease is Familial prostate cancer.