IL1B and myeloid sarcoma: An interesting study performed by exposing mice brain slices to MS patients’ cerebrospinal fluid revealed that transient receptor potential vanilloid 1 (TRPV1), a cation channel known to facilitate glutamatergic neurotransmission, is essential in mediating NMDAR-mediated neurotransmission and excitotoxicity induced by IL-1β during the chronic phase of the disease [107].