Females with AD had significantly higher frontal, parietal and posterior cingulate cortex/ precuneus as well as Braak-stage I, Braak-stage II, Braak-stage III, Braak-stage IV and Braak-stage V TSPO-PET z-scores when compared to female controls, whereas males with AD only comprised higher Braak-stage III TSPO-PET z-scores in the contrast against male controls (Fig. 1, Table 2). Here, TSPO is linked to Alzheimer disease.