TSPO and Alzheimer disease: Similar to a recent multi-center TSPO-PET study in cognitively healthy men and women [11], we observed an effect of sex on the cortical TSPO-PET signal in our cohort, indicating that female patients with AD have higher TSPO-PET signals in frontal, temporal, parietal and posterior cingulate cortices as well as in Braak-stage II, IV and VI regions compared to male patients with AD.