Plectin is involved in the regulation of AF dynamics [64], and, as shown for skeletal muscle, it interacts directly with ß-dystroglycan via multiple domains and with dystrophin/utrophin via its ABD [52]; binding to the ß-dystroglycan/utrophin complex has also been shown for Schwann cells [17]. The gene discussed is UTRN; the disease is atrial fibrillation.