In human pancreatic cancer cell lines PANC-1 and MIA-PaCa-2 cells, as well as murine pancreatic cancer line Pan02, C150 causes ER stress and subsequently increase the assembly and activity of proteasomes and the degradation of transcription factors involved in the epithelial mesenchymal transition (EMT-TF). This evidence concerns the gene TF and familial pancreatic carcinoma.