In the realm of tumor microenvironment (TME) analysis, we ascertained that the immune score, stromal score, and Estimation of Stromal and Immune cells in Malignant Tumor tissues using Expression data (ESTIMATE) score in the BANF1 high-expression cohort markedly lagged those in the BANF1 low-expression group, as exemplified in Figure 6D (p < 0.05). The gene discussed is BANF1; the disease is neoplasm.