The 2016 WHO Histological Classification of Renal Tumors classifies renal cell carcinoma into 16 subtypes; one subtype is Mit family translocation RCC [8], which mainly consists of Xp11.2 translocation /TFE3 gene fusions RCC, TFEB/t (6;11) translocation RCC, and MITF translocation RCC [20, 21], which share similar clinical features, histological, immunohistochemical, and molecular genetic characteristics, but are significantly different from other RCC. The gene discussed is MITF; the disease is renal cell carcinoma.