Prior studies reported success for patients with uncomplicated bacteremia switching to oral treatment within 3 to 5 days.20,21 Current guidelines22 recommend a total treatment duration of 7 days for uncomplicated gram-negative bacteremia, and a recent study suggested that 5 days of treatment for patients showing clinical response guided by CRP values may be sufficient in the treatment of gram-negative bacteremia.23 As the eligibility criteria in our cohort required patients to achieve clinical stability before day 5, a cutoff prior to day 5 may seem more reasonable. Here, CRP is linked to bacterial infectious disease with sepsis.