AGXT2 and diabetes mellitus: AGXT2 single-nucleotide polymorphisms (SNPs) are related to systemic diseases [coronary artery disease (Amir et al. 2018), carotid atherosclerosis (Yoshino et al. 2014b), chronic heart failure (Hu et al. 2016), diabetes mellitus (DM) (Kumon et al. 2022), and mild cognitive impairment (Granot-Hershkovitz et al. 2023)] and biological parameters [blood pressure, sugar, and creatinine (Yoshino et al. 2021)].