HSD17B14 and metabolic dysfunction-associated steatotic liver disease: We also demonstrated that the eight target gut bacteria mainly regulate the expression of three key genes in the liver during NAFLD: CSF2RB, HSD17B14, and FUT2. Compared with the control group, intrahepatic CSF2RB mRNA expression increased in the NAFLD group, whereas that of HSD17B14 and FUT2 decreased.