ENO1 and RAC1 also showed high levels of expression in EGFR mutant LUADs (Figure 3D) aligning with previous studies demonstrating that ENO1 expression is greater in LUAD tumor samples relative to non-cancerous tissue, and the RAC1 splice variant RAC1B enhances LUAD tumor formation in vivo (79, 80). This evidence concerns the gene ENO1 and neoplasm.