In sensitivity analyses, which excluded the outliers (defined as > 3SD ofthe mean), the expression of the inflammasome genes, NLRC4 andNLRP3, were no longer significantly different between the groups (Fig. 1; Table 1).All three ER stress genes (XBP1u, XBP1s, ATF4) remained significantlyincreased in the MDD group compared to the HC group (p = 0.045, 0.005,0.025, respectively, uncorrected; Fig. 2; Table 1), but only XBP1s(p = 0.040, corrected; Table 1)remained significant after FDR correction. Here, NLRC4 is linked to major depressive disorder.