Tests for the interaction between TyG index Q2 group (P for interaction=0.079), Q3 group (P for interaction=0.077), and age and risk of prostate cancer, as well as TyG index Q3 group (P for interaction=0.100) and initial PSA and risk of prostate cancer, were not significant Table 3. This evidence concerns the gene KLK3 and Familial prostate cancer.