The statistically significant indicators in Table 2 were analyzed by univariate binary logistic regression, and the differences between the two groups in age, weight gain during pregnancy, pre-pregnancy BMI, history or family history of PE, family history of hypertension, diabetes mellitus in pregnancy, history of renal disease, PLGF, and DCN, UA, and LDH were statistically significant. The gene discussed is PGF; the disease is diabetes mellitus.