Meleshko et al. (22) designed a personalized diet that significantly reduced TNF-α levels (−6.9 ± 0.91 pg/mL, P < 0.05), along with IL-6 and IL-1, indicating the efficacy of dietary interventions rich in dietary fiber and phytochemicals in improving inflammation levels in T2DM. The gene discussed is TNF; the disease is type 2 diabetes mellitus.