CD8A and viral encephalitis: In the literature, there are also cases of inflammation extended to the trunk, limbic system, and cerebellum, characterized by astrocyte damage, macrophage/microglia activation, and diffuse and scattered infiltrates of cytotoxic T lymphocytes (e.g., CD8+ at hippocampal level), where the extraction of CAR-T cell DNA from the most affected areas has allowed a causal correlation (CAR-T—brain damage, concluding for CAR-T-cell-triggered encephalitis) (40).