In addition, tumor-expressed CD24 promotes immune evasion by interacting with the inhibitory receptor sialic acid-binding Ig-like lectin 10 (Siglec-10) expressed as an anti-phagocytic signal by tumor-associated macrophages (TAMs) (Barkal et al., 2019; Cheng et al., 2021). The gene discussed is CD24; the disease is neoplasm.