In contrast to the control mice, mice with pulmonary fibrosis exhibited notably higher levels of lung proteins such as TGF-βR2, SKP-1, CHI3L1, OGG1, and Galectin-3, alongside lower expression of p-4Ebp1, SARA, p-P70S6K, and PP2A. This evidence concerns the gene SKP1 and pulmonary fibrosis.