Compared with the control group, the BLM-induced pulmonary fibrosis group exhibited significantly higher expression of Fmod and Tgfbr2 mRNA; in contrast, the mRNA expression levels of Bambi, Skp1, Zfyve9, Zfyve16, Ppp2ca, Ppp2r1a, Ppp2r1b, Rps6kb1, and Rps6kb2 were markedly lower. The gene discussed is ZFYVE9; the disease is pulmonary fibrosis.