Interestingly, our data showed that genes known to be associated with pulmonary fibrosis (ANKRD11, CTNNB1, CXCR4, HIF1A, HMGB1, ITSN2, LITAF, NEAT1, VEGFA, and DSE) (77–84) were upregulated in MLCs. The gene discussed is HMGB1; the disease is pulmonary fibrosis.