PTGS2 and colitis: Study by Choi et al. [26] in 2019 concluded that in lipopolysaccharide-induced RAW264.7 cells and a dextran sulfate sodium (DSS)-induced colitis animal model, the effects of probiotics are as follows: Lactobacillus plantarum CAU1064, CAU1031, CAU1273, and CAU1054 strains have nitric oxide (NO) and cyclooxygenase-2 (COX-2) suppression potential.