In comparison, in adult mice Nfatc2 does not appear to be significantly upregulated by cardiomyocytes following myocardial infarction (Supplementary Figures S2B,C), however there is a significant increase in the cardiomyocyte expression of Nppb in infarcted mouse hearts (Supplementary Figures S3B,C). This evidence concerns the gene NFATC2 and myocardial infarction.