In another STZ-induced model for DM using male Sprague–Dawley rats, MIAT was found to function as a sponge for miR-22-3p and regulate the expression of death-associated protein kinase 2 (DAPK2) (172), promoting cardiac fibrosis through the PI3K/Akt signaling pathway (173). Here, DAPK2 is linked to diabetes mellitus.